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Protagonist Reports Positive Top Line Results From Phase 2b Study of Icotrokinra Showing Potential to Transform the Treatment Paradigm for Patients With Ulcerative Colitis
Clinical response rate of 63.5% and clinical remission rate of 30.2% achieved at Week 12 with the highest dose, which continued to improve through Week 28All three doses met the primary endpoint of clinical response at Week 12, with a favorable safety profileThese results in ulcerative colitis build on strong data recently reported for the plaque psoriasis Phase 3 program

Fresh Vine Wine, Inc. (NYSE: VINE) Completes the Acquisition of Amaze Software, Inc., Combined Companies Set to Transform the Creator Economy
CHARLOTTE, NC AND NEWPORT BEACH, CA / ACCESS Newswire / March 10, 2025 / Fresh Vine Wine, Inc. (NYSE American:VINE) today announced the completion of the acquisition of Amaze Software, Inc., This transaction marks a pivotal moment for Vine and Amaze and the creator economy at large, introducing diverse product offerings and innovative, creator-driven brand engagement opportunities.

Syria security forces disperse rival protests in Damascus
Syrian security forces on Sunday fired in the air to disperse rival protests after pro-government demonstrators clashed with a gathering mourning dead civilians, following the reported mass killings of Alawites.

Wild weather blacks out 300,000 properties in Australia
Gusts and torrential rain have blacked out more than 300,000 properties and swamped parts of Australia's east coast, officials said Sunday, with one driver confirmed dead and a dozen troops injured in the wild weather.

Man with Palestinian flag arrested after scaling London's Big Ben
A man who scaled London's Big Ben, and spent the day perched on the historic clock tower with a Palestinian flag, was arrested shortly after he came down after midnight Sunday, police said.

CTT Pharma Uplists to the OTCQB Today
TAMPA, FL / ACCESS Newswire / March 9, 2025 / CTT Pharmaceutical Holdings, Inc. (OTCQB:CTTH) has entered the OTCQB Market today under the ticker symbol "CTTH". CTT Pharma's CEO will issue a news release to shareholders this Wednesday March 12, 2025.

Argentina port city 'destroyed' by massive rainstorm, 13 dead
Argentina's port city of Bahia Blanca has been "destroyed" after being pummeled by a year's worth of rain in a matter of hours, killing 13 and driving hundreds from their homes, authorities said Saturday.

Protesters rally on International Women's Day, fearing far right
Protesters took to the streets across the world Saturday to mark International Women's Day, demanding equal pay, political representation and an end to gender-based violence while voicing fears of rising repression.

Pope responding well to pneumonia treatment, Vatican says
Pope Francis is responding well to treatment for pneumonia after three weeks in hospital, the Vatican said Saturday, adding that the 88-year-old was showing "a gradual, slight improvement".

Sleeping man is struck by train in Peru but survives
An apparently drunken man somehow survived after being struck Saturday by a cargo train while sleeping along train tracks in Peru, local authorities said.

WhatsApp group admin shot dead for allegedly removing member
A Pakistani man has been charged with murder after allegedly shooting the administrator of a community WhatsApp group who removed him from the chat, police said Saturday.

Families of MH370 victims in China seek end to decade of 'torment'
Relatives of Chinese passengers lost on Malaysia Airlines flight MH370 gathered in Beijing on Saturday seeking answers from authorities 11 years after the plane disappeared in one of aviation's greatest enduring mysteries.

Ten dead, hundreds evacuated in Argentina floods
At least ten people were killed and more than a thousand evacuated in the Argentine port city of Bahia Blanca on Friday as torrential rains flooded homes and hospitals, destroyed roads and forced officials to cut power.

Icotrokinra Clinical Study Results Demonstrate Its Potential to Shift Treatment Paradigm and Set a New Standard for Treatment in Plaque Psoriasis
Nearly half of patients with moderate-to-severe plaque psoriasis (PsO) treated with icotrokinra achieved completely clear skin (IGA 0) at Week 24 in Phase 3 ICONIC-LEAD studyTopline results from Phase 3 ICONIC-ADVANCE 1&2studies show icotrokinra achieved co-primary endpoints and showed superiority to deucravacitinib in moderate-to-severe PsOResults pave the way to initiate the first-ever head-to-head study (ICONIC-ASCEND) seeking to demonstrate the superiority of a pill versus injectable biologic in moderate-to-severe PsO

US carries out first firing squad execution since 2010
A South Carolina man convicted of murdering his ex-girlfriend's parents was put to death by firing squad on Friday in the first such execution in the United States in 15 years, prison officials said.

Son of Mexican drug lord sentenced to life in US prison
A top leader of Mexico's violent Jalisco New Generation cartel was sentenced to life in US prison Friday for his bloody role in creating one of the world's most powerful drug syndicates.

'Desperate' son of Hong Kong's jailed Jimmy Lai asks to meet UK PM
The son of jailed Hong Kong media mogul Jimmy Lai has called for an urgent meeting with Britain's Prime Minister Keir Starmer, saying he was "desperate" as his father's defence drew to a close in a high-profile trial.

Colombian FARC dissidents take 29 soldiers, police captive
Dissident members of Colombia's FARC rebel group have taken 29 soldiers and police officers captive during clashes with the military in a key cocaine-growing region in the southwest, the defense ministry said Friday.

Tears, ruined plans as WWII bomb halts Paris-London trains
From missed funerals to scrambled birthday plans, the travellers caught in the cancellation Friday of Paris-London trains were left bewildered and, in some cases, in tears.

Pope marks three weeks in hospital with breathless audio message
Pope Francis's condition remained stable but complex on Friday as he battles pneumonia in hospital, the Vatican said, a day after releasing an audio message in which the 88-year-old sounded weak and breathless.

Thousands stranded as WWII bomb paralyses Paris train station
The unearthing of a 500-kilogram World War II bomb near tracks outside Paris on Friday halted traffic and stranded thousands of passengers in one of the biggest rail disruptions in the French capital in years.

Philippines set to sign visiting forces deal with Canada
The Philippines and Canada have negotiated a deal for the deployment of troops, Manila said Friday, it what will be once signed the latest security pact in the face of increasingly tense confrontations with China.

Pope marks three weeks in hospital, releases audio message
Pope Francis marked three weeks battling double pneumonia in hospital on Friday, reported by the Vatican to be "stable" but sounding weak and breathless in his first audio message.

Impeached South Korea president still in detention despite court order
A South Korean court cancelled the arrest warrant of impeached President Yoon Suk Yeol on Friday, but he remains behind bars with the prosecution likely to appeal.

Now a believer, Trump hosts White House crypto summit
Donald Trump on Friday hosts top cryptocurrency players at the White House, a political boost for an industry that has struggled to gain legitimacy -- and where the Republican president faces conflict of interest concerns.

Japan wildfire evacution orders partially lifted
Japan partially lifted wildfire evacuation orders on Friday after rain helped stop the country's worst blaze in more than half a century from spreading.

Impeached South Korean president still in detention despite court order
A South Korean court cancelled the arrest warrant of impeached President Yoon Suk Yeol on Friday, but he remains behind bars with the prosecution likely to appeal.

One dead, seven missing in Indonesia floods and landslides
Floods and landslides on Indonesia's main island of Java killed one and left seven more missing after heavy rains inundated more than a dozen towns, an official said Friday.

'Eerie' sky, charred bodies: 80 years since Tokyo WWII firestorm
On her sixth birthday 80 years ago, Shizuko Nishio clung to her mother as US B-29 bombers started a firestorm that turned humans to ash and Tokyo into a wasteland.

Australians told 'prepare for worst' as tropical cyclone nears
Violent winds toppled power lines Friday as a tropical cyclone inched towards Australia's eastern coast, sparking evacuation orders and leaving more than 50,000 homes without electricity.

Ainos Reports Full Year 2024 Financial Results
Unveiled revolutionary AI Nose for robotics application, inviting global robotics companies to join Ainos Alliance in shaping the future of smell-enabled robotsAdvanced VELDONA® development with key Japan patent, Taiwan Tanabe partnership, and IRB approval for Sjögren's syndrome clinical study

Organto Announces Reinstatement of Trading on the TSX Venture Exchange
TORONTO, ON and BREDA, NETHERLANDS / ACCESS Newswire / March 7, 2025 / Organto Foods Inc. (TSX-V:OGO)(OTC PINK:OGOFF) ("Organto" or the "Company"), a leading provider of organic and non-GMO fruit and vegetable products, is pleased to announce that the TSX Venture Exchange (the "TSXV" or the "Exchange") has accepted its application for reinstatement of trading of the Company's common shares on the TSXV. This follows the successful resolution of the Failure-to-File Cease Trade Order (the "FFCTO") issued by the British Columbia Securities Commission (the "BCSC") on July 16, 2024, and revoked on January 2, 2025. The Company expects its common shares to be reinstated for trading shortly.